Effectiveness of Anise Oil for Treatment of Mild to Moderate Depression in Patients With Irritable Bowel Syndrome : A Randomized Active and Placebo-Controlled Clinical Trial
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Media type:
E-Article
Title:
Effectiveness of Anise Oil for Treatment of Mild to Moderate Depression in Patients With Irritable Bowel Syndrome : A Randomized Active and Placebo-Controlled Clinical Trial
:
A Randomized Active and Placebo-Controlled Clinical Trial
Published in:Journal of Evidence-Based Complementary & Alternative Medicine
Language:
English
DOI:
10.1177/2156587216628374
ISSN:
2156-5872;
2156-5899
Origination:
Footnote:
Description:
<jats:p> Depression is a prevalent disorder among patients suffering from irritable bowel syndrome. The current study was performed to evaluate the effect of a traditional Persian medicine product, anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome. In a randomized double-blinded active and placebo controlled clinical trial, 120 participants with mild to moderate depression according to the Beck Depression Inventory–II total scores were categorized into 3 equal groups and received anise oil, Colpermin, and placebo. The results at the end of trial (week 4) and follow-up (week 6) demonstrated significant priority against active and placebo groups. Although the mechanism is unknown yet, anise oil could be a promising choice of treatment for depressed patients with irritable bowel syndrome. </jats:p>