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Media type:
E-Article
Title:
Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis
Contributor:
Zhang, Kejian;
Chandrakasan, Shanmuganathan;
Chapman, Heather;
Valencia, C. Alexander;
Husami, Ammar;
Kissell, Diane;
Johnson, Judith A.;
Filipovich, Alexandra H.
imprint:
American Society of Hematology, 2014
Published in:Blood
Language:
English
DOI:
10.1182/blood-2014-05-573105
ISSN:
0006-4971;
1528-0020
Origination:
Footnote:
Description:
<jats:title>Key Points</jats:title>
<jats:p>Synergistic effects were observed in the granule mediated lymphocyte cytotoxicity. Digenic pathogenesis contributed to the development of hemophagocytic lymphohistiocytosis.</jats:p>