> Details

Schulze, Isabell; Rohde, Christian; Scheller-Wendorff, Marina; Bäumer, Nicole; Krause, Annika; Herbst, Friederike; Riemke, Pia; Hebestreit, Katja; Tschanter, Petra; Lin, Qiong; Linhart, Heinz; Godley, Lucy A.; Glimm, Hanno; Dugas, Martin; Wagner, Wolfgang; Berdel, Wolfgang E.; Rosenbauer, Frank; Müller-Tidow, Carsten

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

Reference
management

Bookmarks

Remove from
bookmarks

Share this on Whatsapp

Close

Bookmarks



You can manage bookmarks using lists, please log in to your user account for this.
  • Media type: E-Article
  • Title: Increased DNA methylation of Dnmt3b targets impairs leukemogenesis
  • Contributor: Schulze, Isabell; Rohde, Christian; Scheller-Wendorff, Marina; Bäumer, Nicole; Krause, Annika; Herbst, Friederike; Riemke, Pia; Hebestreit, Katja; Tschanter, Petra; Lin, Qiong; Linhart, Heinz; Godley, Lucy A.; Glimm, Hanno; Dugas, Martin; Wagner, Wolfgang; Berdel, Wolfgang E.; Rosenbauer, Frank; Müller-Tidow, Carsten
  • Published: American Society of Hematology, 2016
  • Published in: Blood, 127 (2016) 12, Seite 1575-1586
  • Language: English
  • DOI: 10.1182/blood-2015-07-655928
  • ISSN: 0006-4971; 1528-0020
  • Origination:
  • Footnote:
  • Description: Key PointsIncreased gene body methylation inhibits leukemia, and oncogenes require varying levels of DNA methylation for efficient leukemogenesis. Dnmt3b-induced DNA methylation in mice targets stem cell–associated genes with prognostic association in acute myeloid leukemia patients.
  • Access State: Open Access