Published in:
Blood, 123 (2014) 17, Seite 2663-2672
Language:
English
DOI:
10.1182/blood-2013-10-532200
ISSN:
1528-0020;
0006-4971
Origination:
University thesis:
Footnote:
Description:
<jats:title>Key Points</jats:title>
<jats:p>Increased mitochondrial ROS production, adaptation to intrinsic oxidative stress, and mitochondrial biogenesis are interconnected in CLL. Targeting the respiratory chain and promoting mitochondrial ROS lead to selective cytotoxicity in CLL cells.</jats:p>