> Details

Lasch, Manuel; Kleinert, Eike Christian; Meister, Sarah; Kumaraswami, Konda; Buchheim, Judith-Irina; Grantzow, Tobias; Lautz, Thomas; Salpisti, Sofia; Fischer, Silvia; Troidl, Kerstin; Fleming, Ingrid; Randi, Anna M.; Sperandio, Markus; Preissner, Klaus T.; Deindl, Elisabeth

Extracellular RNA released due to shear stress controls natural bypass growth by mediating mechanotransduction in mice

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  • Media type: E-Article
  • Title: Extracellular RNA released due to shear stress controls natural bypass growth by mediating mechanotransduction in mice
  • Contributor: Lasch, Manuel; Kleinert, Eike Christian; Meister, Sarah; Kumaraswami, Konda; Buchheim, Judith-Irina; Grantzow, Tobias; Lautz, Thomas; Salpisti, Sofia; Fischer, Silvia; Troidl, Kerstin; Fleming, Ingrid; Randi, Anna M.; Sperandio, Markus; Preissner, Klaus T.; Deindl, Elisabeth
  • imprint: American Society of Hematology, 2019
  • Published in: Blood
  • Language: English
  • DOI: 10.1182/blood.2019001392
  • ISSN: 0006-4971; 1528-0020
  • Origination:
  • Footnote:
  • Description: <jats:title>Key Points</jats:title><jats:p>Shear stress–induced release of RNA from endothelial cells is crucial for initiation of arteriogenesis by controlling mechanotransduction. Extracellular RNA is essential for VWF release from endothelial cells initiating the inflammatory process driving arteriogenesis.</jats:p>
  • Access State: Open Access