• Media type: E-Article
  • Title: Ophthalmic complications during the dengue epidemic in Reunion Island in 2020: a case series and review of the literature
  • Contributor: Mbu-Nyamsi, Digé; Vincent, Muriel; Perez-Fontana, Mariane; Best, Anne-Laurence; Mesnard, Charles; Villeroy, Fréderic; Foucher, Aurélie; Raffray, Loic; Terrier, Cécile Saint-Pastou; Bertolotti, Antoine
  • imprint: Springer Science and Business Media LLC, 2023
  • Published in: BMC Infectious Diseases, 23 (2023) 1
  • Language: English
  • DOI: 10.1186/s12879-023-08432-4
  • ISSN: 1471-2334
  • Keywords: Infectious Diseases
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title><jats:sec> <jats:title>Introduction</jats:title> <jats:p>Dengue is an arboviral disease transmitted by the dengue virus, whose vectors are <jats:italic>Aedes aegypti</jats:italic> and <jats:italic>Aedes albopictus</jats:italic>. The acute phase with its cohort of well-known symptoms is usually spontaneously favorable. Since 2020 in Reunion Island, a new symptom has appeared: the ocular damage of dengue fever, which has already been described in South Asia and South-East Asia. We therefore decided to describe the clinical, biological, ophthalmological, therapeutic, and outcomes of patients with ocular manifestations during dengue fever in Reunion Island in 2020.</jats:p> </jats:sec><jats:sec> <jats:title>Patients and methods</jats:title> <jats:p>This was a retrospective observational study. Patients were included from January 2020 to August 2020 and then reassessed by teleconsultation 1 year later. The patients were identified from the French public health surveillance network by all ophthalmologists on the island. Medical data were collected directly from medical records.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Twenty-eight patients were included. The mean age was 41.9 years. Ocular involvement occurred approximately 9.2 days after the onset of dengue symptoms. The main symptoms were scotoma (71.4%) and sudden decrease of visual acuity (39.2%). Eighteen patients (64.2%) had macular involvement. Fourteen patients were treated with oral or intravenous corticosteroids. Twenty-two (78.5%) patients were evaluated by telephone one year later. Scotoma and decreased visual acuity persisted in 15 patients. Thirteen patients (59%) were bothered by night driving, 32% of patients had reading difficulties and 27% of patients became sensitive to prolonged exposure to screens. </jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Ocular complications of dengue require early and collegial management to limit the risk of long-term sequelae. Further studies on the characteristics and complications of dengue fever are needed to better understand this disease.</jats:p> </jats:sec>
  • Access State: Open Access