• Media type: E-Article
  • Title: Granulation tissue-type hemangioma in a 6-week-old puppy – a case report
  • Contributor: Müller, Janina; Henrich, Manfred; Hoogen-Merkel, Johanna; Hartung, Svenja
  • imprint: Springer Science and Business Media LLC, 2022
  • Published in: BMC Veterinary Research
  • Language: English
  • DOI: 10.1186/s12917-022-03503-1
  • ISSN: 1746-6148
  • Keywords: General Veterinary ; General Medicine
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Hemangioma is a well-known neoplasia in veterinary and human medicine. Several subtypes have been described and are distinguished based on their histologic appearance. The classification schemes of hemangiomas in human and veterinary medicine are different, and various purpose-based schemes can be found in the literature.</jats:p></jats:sec><jats:sec><jats:title>Case presentation</jats:title><jats:p>A six-week-old puppy was presented that suffered from a neoplasia that extended to the musculature of the hind limb. After surgical excision, the mass was submitted for pathohistological examination. The mass was composed of endothelial cells forming vascular slits admixed with a fibrous stroma and spindle cells. Immunohistological examination was positive for factor VIII-related antigen and smooth muscle actin, supporting the diagnosis of hemangioma.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>The final diagnosis of granulation tissue-type hemangioma was given due to the histological appearance of the neoplasia. Granulation tissue-type hemangioma is a rare subtype of hemangioma. In this case an uncommonly young dog was affected.</jats:p></jats:sec>
  • Access State: Open Access