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PETKOV, VENTZISLAV; GENTSCHEVA, TEMENUSCHKA; SCHAMBERGER, CHANTAL; HABERL, INES; ARTL, ANDREAS; ANDREAE, FRITZ; MOSGOELLER, WILHELM

The Vasoactive Intestinal Peptide Receptor Turnover in Pulmonary Arteries Indicates an Important Role for VIP in the Rat Lung Circulation

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  • Media type: E-Article
  • Title: The Vasoactive Intestinal Peptide Receptor Turnover in Pulmonary Arteries Indicates an Important Role for VIP in the Rat Lung Circulation
  • Contributor: PETKOV, VENTZISLAV; GENTSCHEVA, TEMENUSCHKA; SCHAMBERGER, CHANTAL; HABERL, INES; ARTL, ANDREAS; ANDREAE, FRITZ; MOSGOELLER, WILHELM
  • Published: Wiley, 2006
  • Published in: Annals of the New York Academy of Sciences, 1070 (2006) 1, Seite 481-483
  • Language: English
  • DOI: 10.1196/annals.1317.066
  • ISSN: 0077-8923; 1749-6632
  • Keywords: History and Philosophy of Science ; General Biochemistry, Genetics and Molecular Biology ; General Neuroscience
  • Origination:
  • Footnote:
  • Description: Abstract:  Vasoactive intestinal peptide (VIP) is a potent vasorelaxing peptide that plays a role in lung physiology and possibly in pulmonary hypertension. We investigated the turnover of the VIP receptors on rat pulmonary arteries ex vivo. There was evidence for a fast receptor turnover in pulmonary arteries, which underlines the important role of VIP for the regulation of pulmonary circulation and pulmonary pathology.