Moore, Kelly E.;
Santiago Rivera, Olga J.;
Anderson, Bradley;
Johnson, Jennifer E.;
Hahn, Judith A.;
Kurth, Megan E.;
Reddy, Madhavi K.;
Schonbrun, Yael C.;
Stein, Michael D.
Phosphatidylethanol Levels Among Incarcerated Women: The Influence of Pre‐incarceration Alcohol Consumption and Length of Abstinence
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Media type:
E-Article
Title:
Phosphatidylethanol Levels Among Incarcerated Women: The Influence of Pre‐incarceration Alcohol Consumption and Length of Abstinence
Contributor:
Moore, Kelly E.;
Santiago Rivera, Olga J.;
Anderson, Bradley;
Johnson, Jennifer E.;
Hahn, Judith A.;
Kurth, Megan E.;
Reddy, Madhavi K.;
Schonbrun, Yael C.;
Stein, Michael D.
imprint:
Wiley, 2018
Published in:Alcoholism: Clinical and Experimental Research
Description:
<jats:sec><jats:title>Background</jats:title><jats:p>Phosphatidylethanol (<jats:styled-content style="fixed-case">PE</jats:styled-content>th) is a direct biomarker for alcohol that is formed shortly after alcohol use and may remain detectable in blood for weeks after alcohol consumption. There is little research on alcohol use factors that influence <jats:styled-content style="fixed-case">PE</jats:styled-content>th elimination, especially among women.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Data were collected from 116 alcohol use‐disordered women who were recently incarcerated. We used a 2‐part model with logistic and linear components to examine whether alcohol consumption in the 2 weeks prior to incarceration and days since last alcoholic drink (operationalized as abstinence days prior to incarceration + days incarcerated) were associated with <jats:styled-content style="fixed-case">PE</jats:styled-content>th detectability (>8 ng/ml) and level (ng/ml) in blood.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Participants reported drinking an average of 10 drinks per day in the 2 weeks prior to incarceration. Days since last drink was negatively associated with <jats:styled-content style="fixed-case">PE</jats:styled-content>th level (odds ratio [OR] = 0.97, 95% confidence interval [CI] = 0.93; 0.99) and being <jats:styled-content style="fixed-case">PE</jats:styled-content>th detectable (<jats:styled-content style="fixed-case">OR</jats:styled-content> = 0.96, 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 0.91; 0.99). Quantity of alcohol consumed prior to jail admission was associated with <jats:styled-content style="fixed-case">PE</jats:styled-content>th detection (<jats:styled-content style="fixed-case">OR</jats:styled-content> = 1.08; 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 1.03; 1.16), but not <jats:styled-content style="fixed-case">PE</jats:styled-content>th level.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Days since last alcoholic drink and drinks per day both influenced <jats:styled-content style="fixed-case">PE</jats:styled-content>th detectability, but only days since last drink predicted <jats:styled-content style="fixed-case">PE</jats:styled-content>th level among a large sample of women with alcohol use disorder in the criminal justice system.</jats:p></jats:sec>