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Media type:
E-Article
Title:
Medication Overuse Headache
Contributor:
Munksgaard, Signe B.;
Jensen, Rigmor H.
Published:
Wiley, 2014
Published in:
Headache: The Journal of Head and Face Pain, 54 (2014) 7, Seite 1251-1257
Language:
English
DOI:
10.1111/head.12408
ISSN:
0017-8748;
1526-4610
Origination:
Footnote:
Description:
BackgroundMedication overuse headache (MOH) affects between 1% and 2% of the general population but is present in up to 50% of patients seen in headache centers. There are currently no internationally accepted guidelines for treatment ofMOH.MethodsA review of the current literature on MOH treatment and pathophysiology.ResultsWe conclude that headache frequency can be reduced to episodic headache in more than 50% of the patients by simple detoxification and information. Approximately half the patients will not have need for prophylactic medication after withdrawal. Pain perception is altered in patients withMOHbut can be restored to a baseline pattern, indicating a reversible mechanism in the central sensitization leading to chronic pain. The great comorbidity with depression and anxiety could be a consequence of the altered serotonin metabolism indicating a reversible and potentially treatable condition.ConclusionIncreased focus onMOHis extremely important, asMOHboth can and should be treated and prevented.MOHis thus a diagnosis that should be considered in all chronic headache patients as the very first step in their management strategy. In the general population, prevention campaigns againstMOHare essential to minimize chronic pain disability.