Vimentin Expression Pattern is Different between the Flank Region and Limb Regions of Somatopleural Mesoderm in the Chicken Embryo : (vimentin/chicken embryo/limb bud/limbness/mesoderm)
: (vimentin/chicken embryo/limb bud/limbness/mesoderm)
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Media type:
E-Article
Title:
Vimentin Expression Pattern is Different between the Flank Region and Limb Regions of Somatopleural Mesoderm in the Chicken Embryo : (vimentin/chicken embryo/limb bud/limbness/mesoderm)
:
(vimentin/chicken embryo/limb bud/limbness/mesoderm)
Description:
<jats:p>It is known that the chicken flank somatopleure also has a limb‐forming potential at early stages of development, but loses this potential later. Molecular changes during this process is, however, not well known. We obtained a monoclonal antibody which reacts to the flank somatopleure, but not to the wing bud, the leg bud and the neck somatopleure in the stage 22 chicken embryo. Further study revealed that this antibody is specific to vimentin. Time course of vimentin expression in the somatopleural mesoderm during the development was studied. It was revealed to be biphasic. Somatopleural mesoderm expressed vimentin at stage 10, but not at stage 16. Flank somatopleural mesoderm began to express vimentin again at stage 18, whereas limb bud mesenchymal cells did not until stage 27. The earlier re‐expression of vimentin at the flank somatopleure suggests that certain physiological changes take place in cells at this region.</jats:p>