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Laurila, Pirkka-Pekka; Soronen, Jarkko; Kooijman, Sander; Forsström, Saara; Boon, Mariëtte R.; Surakka, Ida; Kaiharju, Essi; Coomans, Claudia P.; Van Den Berg, Sjoerd A. A.; Autio, Anu; Sarin, Antti-Pekka; Kettunen, Johannes; Tikkanen, Emmi; Manninen, Tuula; Metso, Jari; Silvennoinen, Reija; Merikanto, Krista; Ruuth, Maija; Perttilä, Julia; Mäkelä, Anne; Isomi, Ayaka; Tuomainen, Anita M.; Tikka, Anna; Ramadan, Usama Abo; [...]

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

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  • Media type: E-Article
  • Title: USF1 deficiency activates brown adipose tissue and improves cardiometabolic health
  • Contributor: Laurila, Pirkka-Pekka; Soronen, Jarkko; Kooijman, Sander; Forsström, Saara; Boon, Mariëtte R.; Surakka, Ida; Kaiharju, Essi; Coomans, Claudia P.; Van Den Berg, Sjoerd A. A.; Autio, Anu; Sarin, Antti-Pekka; Kettunen, Johannes; Tikkanen, Emmi; Manninen, Tuula; Metso, Jari; Silvennoinen, Reija; Merikanto, Krista; Ruuth, Maija; Perttilä, Julia; Mäkelä, Anne; Isomi, Ayaka; Tuomainen, Anita M.; Tikka, Anna; Ramadan, Usama Abo; [...]
  • Published: American Association for the Advancement of Science (AAAS), 2016
  • Published in: Science Translational Medicine, 8 (2016) 323
  • Language: English
  • DOI: 10.1126/scitranslmed.aad0015
  • ISSN: 1946-6234; 1946-6242
  • Origination:
  • Footnote:
  • Description: Deficiency of USF1 protects against obesity, insulin resistance, and cardiovascular disease in mice and humans, and induces brown adipose tissue to burn triglycerides and glucose.