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Attardo, Geoffrey M.; Abila, Patrick P.; Auma, Joanna E.; Baumann, Aaron A.; Benoit, Joshua B.; Brelsfoard, Corey L.; Ribeiro, José M. C.; Cotton, James A.; Pham, Daphne Q. D.; Darby, Alistair C.; Van Den Abbeele, Jan; Denlinger, David L.; Field, Linda M.; Nyanjom, Steven R. G.; Gaunt, Michael W.; Geiser, Dawn L.; Gomulski, Ludvik M.; Haines, Lee R.; Hansen, Immo A.; Jones, Jeffery W.; Kibet, Caleb K.; Kinyua, Johnson K.; Larkin, Denis M.; Lehane, Michael J.; [...]

Genome Sequence of the Tsetse Fly ( Glossina morsitans ): Vector of African Trypanosomiasis

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  • Media type: E-Article
  • Title: Genome Sequence of the Tsetse Fly ( Glossina morsitans ): Vector of African Trypanosomiasis
  • Contributor: Attardo, Geoffrey M.; Abila, Patrick P.; Auma, Joanna E.; Baumann, Aaron A.; Benoit, Joshua B.; Brelsfoard, Corey L.; Ribeiro, José M. C.; Cotton, James A.; Pham, Daphne Q. D.; Darby, Alistair C.; Van Den Abbeele, Jan; Denlinger, David L.; Field, Linda M.; Nyanjom, Steven R. G.; Gaunt, Michael W.; Geiser, Dawn L.; Gomulski, Ludvik M.; Haines, Lee R.; Hansen, Immo A.; Jones, Jeffery W.; Kibet, Caleb K.; Kinyua, Johnson K.; Larkin, Denis M.; Lehane, Michael J.; [...]
  • imprint: American Association for the Advancement of Science (AAAS), 2014
  • Published in: Science
  • Language: English
  • DOI: 10.1126/science.1249656
  • ISSN: 0036-8075; 1095-9203
  • Origination:
  • Footnote:
  • Description: <jats:title>Africa's Bane</jats:title> <jats:p> Tsetse are blood-feeding, fast-flying flies that transmit a range of <jats:italic>Trypanosoma</jats:italic> spp. protozoan pathogens, which cause sleeping sickness in humans and their nagana in their livestock. The <jats:bold> International <jats:italic>Glossina</jats:italic> Genome Initiative </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="380" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1249656">380</jats:related-article> ) sequenced the genome of <jats:italic>Glossina morsitans</jats:italic> and identified the genes for many attributes of the tsetse's remarkable biology, including viviparity and the expression of analogs of mammalian milk proteins. Tsetse are host to several specific symbionts that appear to synthesize essential nutrients for the fly and also to hitherto undiscovered parasitoid-derived viruses. Deeper exploration of this genome will reveal what makes these fly species so host- and trypanosome specific. </jats:p>