> Details
Adams, Mark D.;
Celniker, Susan E.;
Holt, Robert A.;
Evans, Cheryl A.;
Gocayne, Jeannine D.;
Amanatides, Peter G.;
Scherer, Steven E.;
Li, Peter W.;
Hoskins, Roger A.;
Galle, Richard F.;
George, Reed A.;
Lewis, Suzanna E.;
Richards, Stephen;
Ashburner, Michael;
Henderson, Scott N.;
Sutton, Granger G.;
Wortman, Jennifer R.;
Yandell, Mark D.;
Zhang, Qing;
Chen, Lin X.;
Brandon, Rhonda C.;
Rogers, Yu-Hui C.;
Blazej, Robert G.;
Champe, Mark;
[...]
The Genome Sequence of Drosophila melanogaster
Sharing
Reference
management
Direct link
Bookmarks
Remove from
bookmarks
Share this by email
Share this on Twitter
Share this on Facebook
Share this on Whatsapp
- Media type: E-Article
- Title: The Genome Sequence of Drosophila melanogaster
- Contributor: Adams, Mark D.; Celniker, Susan E.; Holt, Robert A.; Evans, Cheryl A.; Gocayne, Jeannine D.; Amanatides, Peter G.; Scherer, Steven E.; Li, Peter W.; Hoskins, Roger A.; Galle, Richard F.; George, Reed A.; Lewis, Suzanna E.; Richards, Stephen; Ashburner, Michael; Henderson, Scott N.; Sutton, Granger G.; Wortman, Jennifer R.; Yandell, Mark D.; Zhang, Qing; Chen, Lin X.; Brandon, Rhonda C.; Rogers, Yu-Hui C.; Blazej, Robert G.; Champe, Mark; [...]
-
imprint:
American Association for the Advancement of Science (AAAS), 2000
- Published in: Science
- Language: English
- DOI: 10.1126/science.287.5461.2185
- ISSN: 0036-8075; 1095-9203
- Keywords: Multidisciplinary
- Origination:
- Footnote:
- Description: <jats:p> The fly <jats:italic>Drosophila melanogaster</jats:italic> is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to higher eukaryotes, including humans. We have determined the nucleotide sequence of nearly all of the ∼120-megabase euchromatic portion of the <jats:italic>Drosophila</jats:italic> genome using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map. Efforts are under way to close the remaining gaps; however, the sequence is of sufficient accuracy and contiguity to be declared substantially complete and to support an initial analysis of genome structure and preliminary gene annotation and interpretation. The genome encodes ∼13,600 genes, somewhat fewer than the smaller <jats:italic>Caenorhabditis elegans</jats:italic> genome, but with comparable functional diversity. </jats:p>