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Media type:
E-Article
Title:
Comment on “Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women”
Contributor:
Brenner, Charles
imprint:
American Association for the Advancement of Science (AAAS), 2021
Published in:Science
Language:
English
DOI:
10.1126/science.abj1696
ISSN:
0036-8075;
1095-9203
Origination:
Footnote:
Description:
<jats:title>Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women</jats:title>
<jats:p>
Yoshino
<jats:italic>et al</jats:italic>
. (Reports, 11 June 2021, p. 1224) have reported that nicotinamide mononucleotide (NMN) increases muscle insulin sensitivity in prediabetic women. However, the 13 women who received NMN had hepatic lipid content of 6.3 ± 1.2%, whereas the 12 in the placebo group had 14.8 ± 2.0% (
<jats:italic>P</jats:italic>
= 0.003). Given that a target of NMN is liver fat clearance, this was not an effectively randomized trial.
</jats:p>