• Media type: E-Article
  • Title: Antimicrobial Susceptibility of Clinical and Environmental Mycobacterium chimaera Isolates
  • Contributor: Mok, Simone; Hannan, Margaret M.; Nölke, Lars; Stapleton, Patrick; O’Sullivan, Niamh; Murphy, Philip; McLaughlin, Anne Marie; McNamara, Eleanor; Fitzgibbon, Margaret M.; Rogers, Thomas R.
  • imprint: American Society for Microbiology, 2019
  • Published in: Antimicrobial Agents and Chemotherapy
  • Language: English
  • DOI: 10.1128/aac.00755-19
  • ISSN: 0066-4804; 1098-6596
  • Keywords: Infectious Diseases ; Pharmacology (medical) ; Pharmacology
  • Origination:
  • Footnote:
  • Description: <jats:p> <jats:named-content content-type="genus-species">Mycobacterium chimaera</jats:named-content> is a slow-growing nontuberculous <jats:italic>Mycobacterium</jats:italic> species belonging to the <jats:named-content content-type="genus-species">Mycobacterium avium</jats:named-content> complex (MAC). It has been identified globally as the cause of a large outbreak of cardiovascular infections following open heart surgery, but it can also cause respiratory infections in individuals with underlying structural pulmonary disease. Invasive <jats:named-content content-type="genus-species">M. chimaera</jats:named-content> infections are associated with poor clinical responses, and the optimal antibiotic treatment regimen for these infections is not known. </jats:p>
  • Access State: Open Access