Foresti, Sergio;
Di Bella, Stefano;
Rovelli, Attilio;
Sala, Alessandra;
Verna, Marta;
Bisi, Luca;
Nisii, Carla;
Gori, Andrea
Tigecycline Lock Therapy for Catheter-Related Bloodstream Infection Caused by KPC-Producing Klebsiella pneumoniae in Two Pediatric Hematological Patients
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Media type:
E-Article
Title:
Tigecycline Lock Therapy for Catheter-Related Bloodstream Infection Caused by KPC-Producing Klebsiella pneumoniae in Two Pediatric Hematological Patients
Contributor:
Foresti, Sergio;
Di Bella, Stefano;
Rovelli, Attilio;
Sala, Alessandra;
Verna, Marta;
Bisi, Luca;
Nisii, Carla;
Gori, Andrea
imprint:
American Society for Microbiology, 2015
Published in:Antimicrobial Agents and Chemotherapy
Description:
<jats:title>ABSTRACT</jats:title>
<jats:p>
Catheter-related bacteremias carry high mortality rates in hematological patients. When a multidrug-resistant microorganism is involved, the catheter should ideally be removed; however, this approach is not always possible. Tigecycline lock therapy was used in two pediatric oncohematological patients with intravascular catheter-related infection due to KPC-producing
<jats:named-content xmlns:xlink="http://www.w3.org/1999/xlink" content-type="genus-species" xlink:type="simple">Klebsiella pneumoniae</jats:named-content>
. The catheter was salvaged in both cases, and the patients were later discharged. Our experience suggests the usefulness of this approach in treating this type of infection.
</jats:p>