• Media type: E-Article
  • Title: Molecular Characterization of the First Telithromycin-Resistant Streptococcus pneumoniae Isolate in Germany
  • Contributor: Reinert, Ralf René; van der Linden, Mark; Al-Lahham, Adnan
  • Published: American Society for Microbiology, 2005
  • Published in: Antimicrobial Agents and Chemotherapy, 49 (2005) 8, Seite 3520-3522
  • Language: English
  • DOI: 10.1128/aac.49.8.3520-3522.2005
  • ISSN: 0066-4804; 1098-6596
  • Keywords: Infectious Diseases ; Pharmacology (medical) ; Pharmacology
  • Origination:
  • Footnote:
  • Description: <jats:title>ABSTRACT</jats:title> <jats:p> A total of 486 <jats:italic>Streptococcus pneumoniae</jats:italic> isolates were collected in 2003 and 2004 in Germany and revealed the following resistance rates: penicillin G (7.2%) and erythromycin A (18.9%). Telithromycin exhibited good in vitro activity (MIC at which 90% of the isolates tested were inhibited, 0.125 μg/ml). However, one <jats:italic>erm</jats:italic> (B)-positive isolate was found to be telithromycin resistant (MIC, 8 μg/ml). </jats:p>
  • Access State: Open Access