• Media type: E-Article
  • Title: Towards Innovative Design and Application of Recombinant Eimeria as a Vaccine Vector
  • Contributor: Tang, Xinming; Liu, Xianyong; Suo, Xun
  • imprint: American Society for Microbiology, 2020
  • Published in: Infection and Immunity
  • Language: English
  • DOI: 10.1128/iai.00861-19
  • ISSN: 0019-9567; 1098-5522
  • Origination:
  • Footnote:
  • Description: <jats:p> Efficient delivery of antigenic cargo to trigger protective immune responses is critical to the success of vaccination. Genetically engineered microorganisms, including virus, bacteria, and protozoa, can be modified to carry and deliver heterologous antigens to the host immune system. The biological vectors can induce a broad range of immune responses and enhance heterologous antigen-specific immunological outcomes. The protozoan genus <jats:italic>Eimeria</jats:italic> is widespread in domestic animals, causing serious coccidiosis. </jats:p>
  • Access State: Open Access