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Langereis, Jeroen D.; van der Pasch, Eva S.; de Jonge, Marien I.

Serum IgM and C-Reactive Protein Binding to Phosphorylcholine of Nontypeable Haemophilus influenzae Increases Complement-Mediated Killing

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  • Media type: E-Article
  • Title: Serum IgM and C-Reactive Protein Binding to Phosphorylcholine of Nontypeable Haemophilus influenzae Increases Complement-Mediated Killing
  • Contributor: Langereis, Jeroen D.; van der Pasch, Eva S.; de Jonge, Marien I.
  • Published: American Society for Microbiology, 2019
  • Published in: Infection and Immunity, 87 (2019) 8
  • Language: English
  • DOI: 10.1128/iai.00299-19
  • ISSN: 0019-9567; 1098-5522
  • Keywords: Infectious Diseases ; Immunology ; Microbiology ; Parasitology
  • Origination:
  • Footnote:
  • Description: Nontypeable Haemophilus influenzae (NTHi) colonizes the human upper respiratory tract without causing disease symptoms, but it is also a major cause of upper and lower respiratory tract infections in children and elderly, respectively. NTHi synthesizes various molecules to decorate its lipooligosaccharide (LOS), which modulates the level of virulence.
  • Access State: Open Access