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Laperche, Syria; Bouchardeau, Françoise; Thibault, Vincent; Pozzetto, Bruno; Vallet, Sophie; Rosenberg, Arielle R.; Roque-Afonso, Anne-Marie; Gassin, Michèle; Stoll-Keller, Françoise; Trimoulet, Pascale; Gault, Elyanne; Chanzy, Bruno; Mercier, Bernard; Branger, Michel; Pawlotsky, Jean-Michel; Henquell, Cécile; Lunel, Françoise; Gaudy-Graffin, Catherine; Alain, Sophie; Chaix, Marie-Laure; Duverlie, Gilles; Izopet, Jacques; Lefrère, Jean-Jacques

Multicenter Trials Need To Use the Same Assay for Hepatitis C Virus Viral Load Determination

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  • Media type: E-Article
  • Title: Multicenter Trials Need To Use the Same Assay for Hepatitis C Virus Viral Load Determination
  • Contributor: Laperche, Syria; Bouchardeau, Françoise; Thibault, Vincent; Pozzetto, Bruno; Vallet, Sophie; Rosenberg, Arielle R.; Roque-Afonso, Anne-Marie; Gassin, Michèle; Stoll-Keller, Françoise; Trimoulet, Pascale; Gault, Elyanne; Chanzy, Bruno; Mercier, Bernard; Branger, Michel; Pawlotsky, Jean-Michel; Henquell, Cécile; Lunel, Françoise; Gaudy-Graffin, Catherine; Alain, Sophie; Chaix, Marie-Laure; Duverlie, Gilles; Izopet, Jacques; Lefrère, Jean-Jacques
  • Published: American Society for Microbiology, 2007
  • Published in: Journal of Clinical Microbiology, 45 (2007) 11, Seite 3788-3790
  • Language: English
  • DOI: 10.1128/jcm.00825-07
  • ISSN: 0095-1137; 1098-660X
  • Keywords: Microbiology (medical)
  • Origination:
  • Footnote:
  • Description: ABSTRACTThis study, involving 20 laboratories and using currently available assays for hepatitis C virus RNA quantification, demonstrated that differences in viral load values are due not to interlaboratory variations but rather to the nature of the assay itself. This underlines the importance of using the same assay in multicenter studies or when monitoring antiviral therapy.
  • Access State: Open Access