Differences in the N Termini of Herpes Simplex Virus Type 1 and 2 gDs That Influence Functional Interactions with the Human Entry Receptor Nectin-2 and an Entry Receptor Expressed in Chinese Hamster Ovary Cells
You can manage bookmarks using lists, please log in to your user account for this.
Media type:
E-Article
Title:
Differences in the N Termini of Herpes Simplex Virus Type 1 and 2 gDs That Influence Functional Interactions with the Human Entry Receptor Nectin-2 and an Entry Receptor Expressed in Chinese Hamster Ovary Cells
Contributor:
Zago, Anna;
Spear, Patricia G.
Published:
American Society for Microbiology, 2003
Published in:
Journal of Virology, 77 (2003) 17, Seite 9695-9699
Language:
English
DOI:
10.1128/jvi.77.17.9695-9699.2003
ISSN:
0022-538X;
1098-5514
Origination:
Footnote:
Description:
ABSTRACT Amino acid differences at seven positions in the N termini of the glycoproteins D (gDs) specified by herpes simplex virus type 1 (HSV-1) and HSV-2 are largely responsible for the significantly higher cell fusion activity of HSV-2 gD with Chinese hamster ovary cells expressing human nectin-2 or only an endogenous hamster receptor.