• Media type: E-Article
  • Title: Acinetobacter baumannii and Cefiderocol, between Cidality and Adaptability
  • Contributor: Stracquadanio, Stefano; Bonomo, Carmelo; Marino, Andrea; Bongiorno, Dafne; Privitera, Grete Francesca; Bivona, Dalida Angela; Mirabile, Alessia; Bonacci, Paolo Giuseppe; Stefani, Stefania
  • imprint: American Society for Microbiology, 2022
  • Published in: Microbiology Spectrum
  • Language: English
  • DOI: 10.1128/spectrum.02347-22
  • ISSN: 2165-0497
  • Keywords: Infectious Diseases ; Cell Biology ; Microbiology (medical) ; Genetics ; General Immunology and Microbiology ; Ecology ; Physiology
  • Origination:
  • Footnote:
  • Description: <jats:p> This work demonstrates the underrated presence of <jats:named-content content-type="genus-species">Acinetobacter baumannii</jats:named-content> heteroresistant subpopulations after exposure of <jats:named-content content-type="genus-species">A. baumannii</jats:named-content> strains to FDC and its instability. Both <jats:named-content content-type="genus-species">A. baumannii</jats:named-content> and FDC are of great interest for the scientific community, as well as for clinicians; the former represents a major threat to public health due to its resistance to antibiotics, with related costs of prolonged hospitalization, and the latter is a novel, promising cephalosporin currently under the magnifying glass. </jats:p>
  • Access State: Open Access