COVID-19 in children with haematological malignancies

Media type: E-Article
Title: COVID-19 in children with haematological malignancies
Contributor: Millen, Gerard Cathal; Arnold, Roland; Cazier, Jean-Baptiste; Curley, Helen; Feltbower, Richard; Gamble, Ashley; Glaser, Adam; Grundy, Richard G; Kirton, Laura; Lee, Lennard Y W; McCabe, Martin G; Palles, Claire; Phillips, Bob; Stiller, Charles A; Varnai, Csilla; Kearns, Pamela
Published: BMJ, 2022
Published in: Archives of Disease in Childhood, 107 (2022) 2, Seite 186-188
Language: English
DOI: 10.1136/archdischild-2021-322062
ISSN: 0003-9888; 1468-2044
Origination:
Footnote:
Description: <jats:sec><jats:title>Background</jats:title><jats:p>Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies.</jats:p></jats:sec><jats:sec><jats:title>Interpretation</jats:title><jats:p>Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.</jats:p></jats:sec>

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