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Media type:
E-Article
Title:
Rare case of T-cell lymphoma presenting as acute myelopathy
Contributor:
Samara, Verena Clarissa;
de Havenon, Adam
Published:
BMJ, 2016
Published in:
BMJ Case Reports (2016), Seite bcr2016217944
Language:
English
DOI:
10.1136/bcr-2016-217944
ISSN:
1757-790X
Origination:
Footnote:
Description:
Acute myelopathy is a rare presentation of systemic T-cell lymphoma. We present the case of a man aged 68 years with a diffuse erythematous maculopapular rash, followed by lower extremity paresthesias and progressive lower extremity weakness. Spinal MRI showed longitudinally extensive T2 hyperintensity with diffuse contrast enhancement. An atypical clonal T-lymphocyte population was identified in cerebrospinal fluid, peripheral blood and bone marrow aspirate, indicating a malignant T-cell lymphoproliferative disorder. The patient was treated with intrathecal and systemic chemotherapy. Unfortunately, he was not responsive to chemotherapy.