• Media type: E-Article
  • Title: Combination therapy protocol for stage iii or iv carcinoma of the oral cavity, oropharynx and hypopharynx
  • Contributor: Schuller, David E.; King, Gerald W.; Smith, Roy E.; Wilson, Henry E.; James, Arthur D.; Batley, Frank
  • Published: Wiley, 1980
  • Published in: The Laryngoscope, 90 (1980) 8, Seite 1263-1272
  • Language: English
  • DOI: 10.1288/00005537-198008000-00002
  • ISSN: 0023-852X; 1531-4995
  • Origination:
  • Footnote:
  • Description: AbstractCombined therapy programs have improved recurrent and nodal metastatic rates but have not controlled distant metastases. A pilot study undertaken at Ohio State University evaluated the feasibility of adding chemotherapy to a combined modality regimen. The first phase determined that the toxicity of a four‐drug combination chemotherapy yielded a favorable risk/benefit ratio and justified its inclusion in a protocol for untreated cancers.