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Media type:
E-Article
Title:
Fibroblast Growth Factor Signaling during Early Vertebrate Development
Contributor:
Böttcher, Ralph T.;
Niehrs, Christof
Published:
The Endocrine Society, 2005
Published in:
Endocrine Reviews, 26 (2005) 1, Seite 63-77
Language:
English
DOI:
10.1210/er.2003-0040
ISSN:
0163-769X;
1945-7189
Origination:
Footnote:
Description:
<jats:p>Fibroblast growth factors (FGFs) have been implicated in diverse cellular processes including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and proliferation. This review presents our current understanding on the roles of FGF signaling, the pathways employed, and its regulation. We focus on FGF signaling during early embryonic processes in vertebrates, such as induction and patterning of the three germ layers as well as its function in the control of morphogenetic movements.</jats:p>