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Aranda, Judit; Oriol, Isabel; Feria, Lucía; Abelenda, Gabriela; Rombauts, Alexander; Simonetti, Antonella Francesca; Catalano, Clarisa; Pallarès, Natàlia; Martín, Miguel; Vàzquez, Núria; Vall-Llosera, Estel; Rhyman, Nicolás; Suárez, Romina Concepción; Nogué, Marta; Loureiro-Amigo, Jose; Coloma, Ana; Ceresuela, Luis; Carratalà, Jordi

Persistent COVID-19 symptoms 1 year after hospital discharge: A prospective multicenter study

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  • Media type: E-Article
  • Title: Persistent COVID-19 symptoms 1 year after hospital discharge: A prospective multicenter study
  • Contributor: Aranda, Judit; Oriol, Isabel; Feria, Lucía; Abelenda, Gabriela; Rombauts, Alexander; Simonetti, Antonella Francesca; Catalano, Clarisa; Pallarès, Natàlia; Martín, Miguel; Vàzquez, Núria; Vall-Llosera, Estel; Rhyman, Nicolás; Suárez, Romina Concepción; Nogué, Marta; Loureiro-Amigo, Jose; Coloma, Ana; Ceresuela, Luis; Carratalà, Jordi
  • imprint: Public Library of Science (PLoS), 2022
  • Published in: PLOS ONE
  • Language: English
  • DOI: 10.1371/journal.pone.0275615
  • ISSN: 1932-6203
  • Origination:
  • Footnote:
  • Description: <jats:sec id="sec001"> <jats:title>Objective</jats:title> <jats:p>To determine the health status and exercise capacity of COVID-19 survivors one year after hospital discharge.</jats:p> </jats:sec> <jats:sec id="sec002"> <jats:title>Methods</jats:title> <jats:p>This multicenter prospective study included COVID-19 survivors 12 months after hospital discharge. Participants were randomly selected from a large cohort of COVID-19 patients who had been hospitalized until 15th April 2020. They were interviewed about persistent symptoms, underwent a physical examination, chest X-ray, and a 6-minute walk test (6MWT). A multivariate analysis was performed to determine the risk factors for persistent dyspnea.</jats:p> </jats:sec> <jats:sec id="sec003"> <jats:title>Results</jats:title> <jats:p>Of the 150 patients included, 58% were male and the median age was 63 (IQR 54–72) years. About 82% reported ≥1 symptoms and 45% had not recovered their physical health. The multivariate regression analysis revealed that the female sex, chronic obstructive pulmonary disease, and smoking were independent risk factors for persistent dyspnea. Approximately 50% completed less than 80% of the theoretical distance on the 6MWT. Only 14% had an abnormal X-ray, showing mainly interstitial infiltrates. A third of them had been followed up in outpatient clinics and 6% had undergone physical rehabilitation.</jats:p> </jats:sec> <jats:sec id="sec004"> <jats:title>Conclusion</jats:title> <jats:p>Despite the high rate of survivors of the first wave of the COVID-19 pandemic with persistent symptomatology at 12 months, the follow-up and rehabilitation of these patients has been really poor. Studies focusing on the role of smoking in the persistence of COVID-19 symptoms are lacking.</jats:p> </jats:sec>
  • Access State: Open Access