Santos, Daniela Corrêa;
Henriques, Ruan Roberto;
Lopes Jr, Marcos Antonio Abreu;
Maia, Paulo José Sousa;
Silva, Andreza Miranda Barata;
Paschoal, Diego Fernando Silva;
Souza, Andréa Luzia Ferreira
Microwave-assisted synthesis, spectral characterization and DFT studies of Zn(II) complexes based on N-acylhydrazone ligands: stability and antioxidant activity
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Media type:
E-Article
Title:
Microwave-assisted synthesis, spectral characterization and DFT studies of Zn(II) complexes based on N-acylhydrazone ligands: stability and antioxidant activity
Contributor:
Santos, Daniela Corrêa;
Henriques, Ruan Roberto;
Lopes Jr, Marcos Antonio Abreu;
Maia, Paulo José Sousa;
Silva, Andreza Miranda Barata;
Paschoal, Diego Fernando Silva;
Souza, Andréa Luzia Ferreira
Published:
Mediterranean Journal of Chemistry, 2023
Published in:
Mediterranean Journal of Chemistry, 13 (2023) 1, Seite 64
Language:
Not determined
DOI:
10.13171/mjc02303071666souza
ISSN:
2028-3997
Origination:
Footnote:
Description:
<p class="03Abstract">This article reports the synthesis of seven Zn(II) complexes containing <em>N</em>-acylhydrazone ligands (<strong>L1 </strong>to<strong> L7</strong>) and the assessment of their antioxidant. Microwave assisted-synthesis of ligands with ZnCl<sub>2</sub> in MeOH yielded tetrahedral Zn(II) complexes with a 1:2 metal: ligand ratio, characterized by HRMS, FTIR, and UV-Vis spectroscopy, thermal and electrochemical analyses, and DFT calculations. The <strong>(L3)<sub>2</sub>Zn</strong> complex exhibited the lowest thermal stability, and <strong>(L6)<sub>2</sub>Zn</strong> and <strong>(L7)<sub>2</sub>Zn</strong> were the most stable. XRD powder showed that all complexes have good crystallinity with crystalline dimensions ranging from 32 to 86 nm. Cyclic voltammetry of Zn(II) complexes indicated a reversible redox process for <strong>(L4)<sub>2</sub>Zn</strong> and an irreversible process for the remaining six complexes: <strong>(L1)<sub>2</sub>Zn </strong>to <strong>(L3)<sub>2</sub>Zn</strong> and <strong>(L5)<sub>2</sub>Zn</strong> to <strong>(L7)<sub>2</sub>Zn</strong>. Antioxidant activity of ligands and complexes was assessed by the DPPH method; the <strong>L7 </strong>ligand and corresponding <strong>(L7)<sub>2</sub>Zn</strong> complex exhibited good activity, IC<sub>50</sub> = 65.30 μmol.l<sup>-1 </sup>and 78.70 μmol.l<sup>-1</sup>, respectively, when compared with standard ascorbic acid. <strong></strong></p>