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Media type:
E-Article
Title:
Microsurgical clipping in forty patients with unruptured anterior cerebral circulation aneurysms: an investigation into cognitive outcome
Contributor:
Pereira-Filho, Arthur A;
Pereira, Adriana G;
Faria, Mário B;
Lima, Leonardo C.S;
Portuguez, Mirna W;
Kraemer, Jorge L
Published:
FapUNIFESP (SciELO), 2010
Published in:
Arquivos de Neuro-Psiquiatria, 68 (2010) 5, Seite 770-774
Language:
Not determined
DOI:
10.1590/s0004-282x2010000500018
ISSN:
0004-282X
Origination:
Footnote:
Description:
<jats:p>OBJECTIVE: It is a consensus that most unruptured intracranial aneurysms (UIA) can be treated with acceptably low morbidity. However, some studies recently reported postoperative cognitive impairment, suggesting that it could be attributable to surgical damage. Our goal is to evaluate cognitive function before and after microsurgical clipping in patients with UIA. METHOD: A consecutive series of 40 patients who underwent microsurgical clipping for UIA were studied. The cognitive assessment (Mini Mental State Examination, MMSE) was performed immediately before and at least one month after surgery. Paired Student's "t" test and analysis of variance (ANOVA) were used for statistical purposes. RESULTS: The mean MMSE score in the preoperative analysis was 28.12 (SD, 1.34). In the postoperative period the mean MMSE score was 28.40 (SD, 1.46). Paired Student's "t" test was applied to the scores and no significant difference was found (p=0.315). ANOVA did not find independent associations between MMSE scores and age, hypertension, smoking, dyslipidemia, education, aneurysm location, number, laterality or size. CONCLUSION: The present study suggests that microsurgical clipping for UIA does not result in major cognitive dysfunction as determined by the MMSE</jats:p>