Cortez-Escalante, Juan José;
Castro, Cleudson;
Romero, Gustavo Adolfo Sierra;
Matos, Luiza;
Saif, Muhammad Wasif
Pulmonary thromboembolism in AIDS patient with chronic venous insufficiency, pulmonary tuberculosis and breast cancer: a case report and pathophysiology review
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Media type:
E-Article
Title:
Pulmonary thromboembolism in AIDS patient with chronic venous insufficiency, pulmonary tuberculosis and breast cancer: a case report and pathophysiology review
Contributor:
Cortez-Escalante, Juan José;
Castro, Cleudson;
Romero, Gustavo Adolfo Sierra;
Matos, Luiza;
Saif, Muhammad Wasif
Published:
FapUNIFESP (SciELO), 2006
Published in:
Revista do Instituto de Medicina Tropical de São Paulo, 48 (2006) 2, Seite 105-108
Description:
Recent literature reports thrombotic episodes occurring in patients with HIV infection associated with other abnormalities including neoplasms and infections predisposing to a hypercoagulable state. We report a 47-year-old woman who developed pulmonary thromboembolism in association with HIV infection, pulmonary tuberculosis and breast cancer. She was treated with rifampin, isoniazid, pyrazinamide; heparin, phenprocoumon, zidovudine, lamivudine and efavirenz. Acid fast bacilli were visualized in a sputum smear and three months after, Mycobacterium tuberculosis was isolated from lymph node biopsy during a episode of immune reconstitution. The isolated mycobacteria showed sensitivity to all first-line drugs. HIV infection, breast cancer and pulmonary tuberculosis have several mechanisms that induce hypercoagulable state and can lead to thromboembolic complications. Pulmonary thromboembolism in this patient was a diagnostic challenge because of all the other severe diseases that she experienced at the same time.