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Hannan, Mary; Ansari, Sajid; Meza, Natalie; Anderson, Amanda H.; Srivastava, Anand; Waikar, Sushrut; Charleston, Jeanne; Weir, Matthew R.; Taliercio, Jonathan; Horwitz, Edward; Saunders, Milda R.; Wolfrum, Katherine; Feldman, Harold I.; Lash, James P.; Ricardo, Ana C.

Risk Factors for CKD Progression : Overview of Findings from the CRIC Study : Overview of Findings from the CRIC Study

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  • Media type: E-Article
  • Title: Risk Factors for CKD Progression : Overview of Findings from the CRIC Study : Overview of Findings from the CRIC Study
  • Contributor: Hannan, Mary; Ansari, Sajid; Meza, Natalie; Anderson, Amanda H.; Srivastava, Anand; Waikar, Sushrut; Charleston, Jeanne; Weir, Matthew R.; Taliercio, Jonathan; Horwitz, Edward; Saunders, Milda R.; Wolfrum, Katherine; Feldman, Harold I.; Lash, James P.; Ricardo, Ana C.
  • imprint: Ovid Technologies (Wolters Kluwer Health), 2021
  • Published in: Clinical Journal of the American Society of Nephrology
  • Language: English
  • DOI: 10.2215/cjn.07830520
  • ISSN: 1555-9041; 1555-905X
  • Origination:
  • Footnote:
  • Description: <jats:p>The Chronic Renal Insufficiency Cohort (CRIC) Study is an ongoing, multicenter, longitudinal study of nearly 5500 adults with CKD in the United States. Over the past 10 years, the CRIC Study has made significant contributions to the understanding of factors associated with CKD progression. This review summarizes findings from longitudinal studies evaluating risk factors associated with CKD progression in the CRIC Study, grouped into the following six thematic categories: (<jats:italic toggle="yes">1</jats:italic>) sociodemographic and economic (sex, race/ethnicity, and nephrology care); (<jats:italic toggle="yes">2</jats:italic>) behavioral (healthy lifestyle, diet, and sleep); (<jats:italic toggle="yes">3</jats:italic>) genetic (apoL1, genome-wide association study, and renin-angiotensin-aldosterone system pathway genes); (<jats:italic toggle="yes">4</jats:italic>) cardiovascular (atrial fibrillation, hypertension, and vascular stiffness); (<jats:italic toggle="yes">5</jats:italic>) metabolic (fibroblast growth factor 23 and urinary oxalate); and (<jats:italic toggle="yes">6</jats:italic>) novel factors (AKI and biomarkers of kidney injury). Additionally, we highlight areas where future research is needed, and opportunities for interdisciplinary collaboration.</jats:p>
  • Access State: Open Access