• Media type: E-Article
  • Title: OPTIC NEUROPATHY INDUCED BY LOW DOSE OF ETHAMBUTOL: A RARE PRESENTATION
  • Contributor: Addoor, Krishna Rao; Janardhana Raju, Vuppalapati Nishant; Bhandary, Sulatha V; Menon, Sudha Girish; Gupta, Aakanksha
  • Published: Innovare Academic Sciences Pvt Ltd, 2017
  • Published in: Asian Journal of Pharmaceutical and Clinical Research, 10 (2017) 4, Seite 12
  • Language: Not determined
  • DOI: 10.22159/ajpcr.2017.v10i4.16983
  • ISSN: 2455-3891; 0974-2441
  • Keywords: Pharmacology (medical) ; Pharmaceutical Science ; Pharmacology
  • Origination:
  • Footnote:
  • Description: Ethambutol is a bacteriostatic antimicrobial agent used in the treatment of tuberculosis. Optic neuropathy is a potentially severe side effect of ethambutol, which is dose related. Ethambutol-induced optic neuropathy (EON) incidence is 15%, 5% & 1% when taken at 50 mg/kg/day , 25 mg/kg/day & 15 mg/kg/day respectively for 3 months. We report a case of bilateral EON in 20-year-old female after 1 month of exposure to 15 mg/kg/day of ethambutol for tubercular meningitis. Ophthalmologic examination revealed bilateral ill sustained pupillary reactions and optic disc pallor. Deranged color vision test and scotomas on Goldmann perimetry in both eyes, aided in diagnosis.Keywords: Low dose ethambutol, Optic neuropathy, Tuberculosis.
  • Access State: Open Access