Description:
<jats:p>
<jats:bold>Aim:</jats:bold>
To assess patient experience with chemotherapy and avelumab in metastatic Merkel cell carcinoma (mMCC).
<jats:bold>Methods:</jats:bold>
In the JAVELIN Merkel 200 trial, chemotherapy-refractory mMCC patients could participate in optional qualitative interviews at baseline documenting recollection of previous chemotherapy experience, and at weeks 13/25 documenting current experience with avelumab. Functional Assessment of Cancer Therapy subscale for melanoma questionnaire (FACT-M) was administered in parallel.
<jats:bold>Results:</jats:bold>
In our sample, chemotherapy was associated with an unpleasant experience. On selected FACT-M items addressing chemotherapy-impacted concepts, most patients receiving avelumab were improved or stable; few worsened. In addition, a few patients spontaneously reported experiencing less toxicity with avelumab than experienced during previous chemotherapy.
<jats:bold>Conclusion:</jats:bold>
This approach merging qualitative and quantitative data suggests that mMCC patients report a better experience with avelumab than with chemotherapy.
</jats:p>