• Media type: E-Article
  • Title: Efficacy of a Day-Care Program in the Treatment of Psoriasis
  • Contributor: Zhang, Junling; Adam, David N.; Stebbing, Elaine; Gerbrandt, Judith; Lui, Harvey; Shapiro, Jerry; Zhou, Youwen
  • imprint: SAGE Publications, 2008
  • Published in: Journal of Cutaneous Medicine and Surgery
  • Language: English
  • DOI: 10.2310/7750.2008.07069
  • ISSN: 1203-4754; 1615-7109
  • Keywords: Dermatology ; Surgery
  • Origination:
  • Footnote:
  • Description: <jats:sec><jats:title>Background:</jats:title><jats:p> Few data exist documenting the effectiveness of psoriasis day-care treatment programs (PDTPs) using standardized efficacy measurements. </jats:p></jats:sec><jats:sec><jats:title>Objectives:</jats:title><jats:p> We sought to analyze the efficacy of a PDTP using the Psoriasis Area and Severity Index (PASI). </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> A retrospective review was performed on 132 patients treated at our PDTP. Sufficient data existed to permit PASI analysis using a simplified method for a representative subgroup of 64 patients, who formed the study population. Patients received phototherapy and topical treatments over 2 weeks. The outcome measures included a baseline and day 11 PASI, a physician global assessment (PGA), and adverse events reported by the patients. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Mean baseline PASI was 13.6 ( N = 64), with a 59.6% reduction by day 11. A PASI reduction of ≥ 50% was seen in 75% of patients, with 30% of patients achieving ≥ 75% reduction of PASI. Day 11 PGA demonstrated a 69.9% improvement. </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> With a reduction in PASI of 59.6% at 11 days, our PDTP, with phototherapy and topical agents, seems to be a rapid and effective therapy for psoriasis. </jats:p></jats:sec>