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Media type:
E-Article
Title:
Systematic approach to celiac disease: a comprehensive review for primary providers
Contributor:
Cortés, Pedro;
Harris, Dana M;
Bi, Yan
imprint:
Walter de Gruyter GmbH, 2022
Published in:Romanian Journal of Internal Medicine
Language:
English
DOI:
10.2478/rjim-2022-0002
ISSN:
2501-062X
Origination:
Footnote:
Description:
<jats:title>Abstract</jats:title>
<jats:p>Celiac disease is an immune-mediated illness to gluten exposure in genetically susceptible patients. It is characterized by chronic lymphocytic inflammation of the small bowel leading to villous atrophy and its associated complications. The global prevalence of celiac disease is increasing, due in part to improved screening tests and simplified diagnostic criteria. Novel therapies are being developed and include proteolytic enzymes, sequestering agents, and immunotherapies. A strict gluten-free diet, however, remains the mainstay of treatment. In this comprehensive review, we discuss the epidemiology, definitions, diagnosis, and treatment of celiac disease.</jats:p>