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Media type:
E-Article
Title:
Wrist-worn device combining PPG and ECG can be reliably used for atrial fibrillation detection in an outpatient setting
Contributor:
Saarinen, Harri Juhani;
Joutsen, Atte;
Korpi, Kirsi;
Halkola, Tuomas;
Nurmi, Marko;
Hernesniemi, Jussi;
Vehkaoja, Antti
imprint:
Frontiers Media SA, 2023
Published in:Frontiers in Cardiovascular Medicine
Language:
Not determined
DOI:
10.3389/fcvm.2023.1100127
ISSN:
2297-055X
Origination:
Footnote:
Description:
<jats:sec><jats:title>Aims</jats:title><jats:p>The aim was to validate the performance of a monitoring system consisting of a wrist-worn device and a data management cloud service intended to be used by medical professionals in detecting atrial fibrillation (AF).</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Thirty adult patients diagnosed with AF alone or AF with concomitant flutter were recruited. Continuous photoplethysmogram (PPG) and intermittent 30 s Lead I electrocardiogram (ECG) recordings were collected over 48 h. The ECG was measured four times a day at prescheduled times, when notified due to irregular rhythm detected by PPG, and when self-initiated based on symptoms. Three-channel Holter ECG was used as the reference.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The subjects recorded a total of 1,415 h of continuous PPG data and 3.8 h of intermittent ECG data over the study period. The PPG data were analyzed by the system’s algorithm in 5-min segments. The segments containing adequate amounts, at least ~30 s, of adequate quality PPG data for rhythm assessment algorithm, were included. After rejecting 46% of the 5-min segments, the remaining data were compared with annotated Holter ECG yielding AF detection sensitivity and specificity of 95.6 and 99.2%, respectively. The ECG analysis algorithm labeled 10% of the 30-s ECG records as inadequate quality and these were excluded from the analysis. The ECG AF detection sensitivity and specificity were 97.7 and 89.8%, respectively. The usability of the system was found to be good by both the study subjects and the participating cardiologists.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>The system comprising of a wrist device and a data management service was validated to be suitable for use in patient monitoring and in the detection of AF in an ambulatory setting.</jats:p><jats:p><jats:bold>Clinical Trial Registration</jats:bold>: <jats:ext-link>ClinicalTrials.gov/</jats:ext-link>, NCT05008601.</jats:p></jats:sec>