You can manage bookmarks using lists, please log in to your user account for this.
Media type:
E-Article
Title:
Epigenetic Aberrations in Multiple Myeloma
Contributor:
Caprio, Cinzia;
Sacco, Antonio;
Giustini, Viviana;
Roccaro, Aldo M.
Published:
MDPI AG, 2020
Published in:
Cancers, 12 (2020) 10, Seite 2996
Language:
English
DOI:
10.3390/cancers12102996
ISSN:
2072-6694
Origination:
University thesis:
Footnote:
Description:
<jats:p>Multiple myeloma (MM) is a plasma cell dyscrasia characterized by proliferation of clonal plasma cells within the bone marrow. Several advances in defining key processes responsible for MM pathogenesis and disease progression have been made; and dysregulation of epigenetics, including DNA methylation and histone modification, has emerged as a crucial regulator of MM pathogenesis. In the present review article, we will focus on the role of epigenetic modifications within the specific context of MM.</jats:p>