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Media type:
E-Article
Title:
Epidemiology of Glioblastoma Multiforme–Literature Review
Contributor:
Grochans, Szymon;
Cybulska, Anna Maria;
Simińska, Donata;
Korbecki, Jan;
Kojder, Klaudyna;
Chlubek, Dariusz;
Baranowska-Bosiacka, Irena
imprint:
MDPI AG, 2022
Published in:Cancers
Language:
English
DOI:
10.3390/cancers14102412
ISSN:
2072-6694
Origination:
Footnote:
Description:
<jats:p>Glioblastoma multiforme (GBM) is one of the most aggressive malignancies, with a median overall survival of approximately 15 months. In this review, we analyze the pathogenesis of GBM, as well as epidemiological data, by age, gender, and tumor location. The data indicate that GBM is the higher-grade primary brain tumor and is significantly more common in men. The risk of being diagnosed with glioma increases with age, and median survival remains low, despite medical advances. In addition, it is difficult to determine clearly how GBM is influenced by stimulants, certain medications (e.g., NSAIDs), cell phone use, and exposure to heavy metals.</jats:p>