• Media type: E-Article
  • Title: Monitoring Therapy Efficiency in Cancer through Extracellular Vesicles
  • Contributor: Stevic, Ines; Buescher, Gustav; Ricklefs, Franz Lennard
  • imprint: MDPI AG, 2020
  • Published in: Cells
  • Language: English
  • DOI: 10.3390/cells9010130
  • ISSN: 2073-4409
  • Keywords: General Medicine
  • Origination:
  • Footnote:
  • Description: <jats:p>Extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed vesicles made of a phospholipid bilayer and are secreted by all cell types. EVs are present in a variety of body fluids containing proteins, DNA, RNA species, and lipids, and play an important role in cell- to-cell communication and are worth being considered as biomarkers for both early diagnosis of cancer patients and real-time monitoring of treatment response. Recently, emerging evidence verified EVs to have crucial roles in cancer progression and metastasis and a great potential in therapeutic applications. In this review, we discuss the potential of EVs in monitoring the efficacy of cancer therapies.</jats:p>
  • Access State: Open Access