Schulz, Marten;
Vuong, Lam Giang;
Müller, Hans Peter;
Maibier, Martin;
Tacke, Frank;
Blau, Igor Wolfgang;
Wree, Alexander
Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
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Media type:
E-Article
Title:
Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
Contributor:
Schulz, Marten;
Vuong, Lam Giang;
Müller, Hans Peter;
Maibier, Martin;
Tacke, Frank;
Blau, Igor Wolfgang;
Wree, Alexander
imprint:
MDPI AG, 2021
Published in:Diagnostics
Language:
English
DOI:
10.3390/diagnostics11060928
ISSN:
2075-4418
Origination:
Footnote:
Description:
<jats:p>Hepatic sinusoidal obstruction syndrome (SOS), also known as veno-occlusive disease (VOD) can be a life-threatening complication after hematopoietic stem cell transplantation (HSCT). Diagnosis is often difficult and traditionally based on clinical parameters. Shear wave elastography (SWE) is a modern non-invasive liver stiffness measurement technique using ultrasound. In this monocentric study, we evaluated the role of SWE in diagnosing SOS/VOD in 63 adult patients undergoing HSCT from February 2020 to August 2020 in real world settings. Three patients developed SOS/VOD. This was accompanied by an increase in shear wave velocity in all three patients, indicating that this method may contribute to establishing the diagnosis SOS/VOD after HSCT.</jats:p>