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Media type:
E-Article
Title:
Cardiovascular Disease and SARS-CoV-2: the Role of Host Immune Response Versus Direct Viral Injury
Contributor:
Biscetti, Federico;
Rando, Maria Margherita;
Nardella, Elisabetta;
Cecchini, Andrea Leonardo;
Bruno, Piergiorgio;
Landolfi, Raffaele;
Flex, Andrea
Published:
MDPI AG, 2020
Published in:
International Journal of Molecular Sciences, 21 (2020) 21, Seite 8141
Language:
English
DOI:
10.3390/ijms21218141
ISSN:
1422-0067
Origination:
Footnote:
Description:
The 2019 novel coronavirus [2019-nCoV], which started to spread from December 2019 onwards, caused a global pandemic. Besides being responsible for the severe acute respiratory syndrome 2 [SARS-CoV-2], the virus can affect other organs causing various symptoms. A close relationship between SARS-CoV-2 and the cardiovascular system has been shown, demonstrating an epidemiological linkage between SARS-CoV-2 and cardiac injury. There are emerging data regarding possible direct myocardial damage by 2019-nCoV. In this review, the most important available evidences will be discussed to clarify the precise mechanisms of cardiovascular injury in SARS-CoV-2 patients, even if further researches are needed.