Effectiveness, Safety and Tolerance of Methotrexate in Vietnamese Psoriatic Arthritis Patients

Media type: E-Article
Title: Effectiveness, Safety and Tolerance of Methotrexate in Vietnamese Psoriatic Arthritis Patients
Contributor: Bui Thi, Van; Ngo Minh, Vinh; Tran Ngoc, Anh; Tran Dang, Quyet; Le Ngoc, Diep; Dang Van, Em; Nguyen Van, Thuong; Thi Minh, Phuong Pham; Thi Thu, Hien Do; Dinh Huu, Nghi; Le Huyen, My; Tran Hau, Khang; Gandolfi, Marco; Satolli, Francesca; Feliciani, Claudio; Tirant, Michael; Vojvodic, Aleksandra; Lotti, Torello
Published: Scientific Foundation SPIROSKI, 2019
Published in: Open Access Macedonian Journal of Medical Sciences, 7 (2019) 2, Seite 250-252
Language: Not determined
DOI: 10.3889/oamjms.2019.063
ISSN: 1857-9655
Keywords: General Medicine
Origination:
Footnote:
Description: AIM: To access the effectiveness, safety and tolerance of methotrexate (MTX) in psoriatic arthritis (PsA) treatment. METHODS: We recruit 37 patients, admitted at HCMC Hospital of Dermato-Venereology from 1/2016 to 3/2017, with MTX dosage ranging from 10 mg to 15 mg per week. RESULTS: Skin lesion response after 12 weeks improved PASI 50: 40.5%, PASI 75: 24.3%. Disease activity score decreased after 12 weeks with ∆DAS28 = -1.43 + 0.79, 37.8% PsA achieved complete remission. Nausea and vomiting were 8.1%. These symptoms were mild and transient. We did not stop MTX usage. The rate of elevating SGPT 2-3 times as much as the upper limit of the normal range was 2.7%. CONCLUSION: We finally demonstrated that the rate of treatment response in Vietnam is the same as demonstrated by foreign authors in other countries.
Access State: Open Access

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