• Media type: E-Article
  • Title: Clinical response of clozapine as a treatment for delirious mania
  • Contributor: Wahid, Nabeel; Chin, Garwin; Turner, Andia H.; Seegan, Alexis
  • Published: Hindawi Limited, 2017
  • Published in: Mental Illness, 9 (2017) 2
  • Language: Without Specification
  • DOI: 10.4081/mi.2017.7182
  • ISSN: 2036-7465; 2036-7457
  • Keywords: Psychiatry and Mental health
  • Origination:
  • Footnote:
  • Description: Delirious mania is an understudied psychiatric disorder with a mortality rate as high as 75%. Previous case studies suggest that electroconvulsive therapy (ECT) may be an effective treatment for delirious mania, though this procedure may not always be a viable option. We describe the case of a 20-year old patient, with no previous psychiatric history, who developed delirious mania over the course of four months. ECT was not a viable option for this patient due to his religious beliefs, so alternative treatment modalities were explored. After failing trials of risperidone and olanzapine, significant improvements in symptoms were exhibited with a trial of clozapine. We propose that clozapine may be an effective option in cases of delirious mania, when ECT is not a viable option. Additional research is still necessary to understand the pathology of this condition and potential treatment modalities.
  • Access State: Open Access