You can manage bookmarks using lists, please log in to your user account for this.
Media type:
E-Article
Title:
Frequency-specific directed interactions in the human brain network for language
Contributor:
Schoffelen, Jan-Mathijs;
Hultén, Annika;
Lam, Nietzsche;
Marquand, André F.;
Uddén, Julia;
Hagoort, Peter
imprint:
National Academy of Sciences, 2017
Published in:Proceedings of the National Academy of Sciences of the United States of America
Language:
English
ISSN:
0027-8424;
1091-6490
Origination:
Footnote:
Description:
<p>The brain’s remarkable capacity for language requires bidirectional interactions between functionally specialized brain regions. We used magnetoencephalography to investigate interregional interactions in the brain network for language while 102 participants were reading sentences. Using Granger causality analysis, we identified inferior frontal cortex and anterior temporal regions to receive widespread input and middle temporal regions to send widespread output. This fits well with the notion that these regions play a central role in language processing. Characterization of the functional topology of this network, using data-driven matrix factorization, which allowed for partitioning into a set of subnetworks, revealed directed connections at distinct frequencies of interaction. Connections originating from temporal regions peaked at alpha frequency, whereas connections originating from frontal and parietal regions peaked at beta frequency. These findings indicate that the information flow between language-relevant brain areas, which is required for linguistic processing, may depend on the contributions of distinct brain rhythms.</p>