• Media type: E-Article
  • Title: The Genome of the Diatom Thalassiosira pseudonana: Ecology, Evolution, and Metabolism
  • Contributor: Armbrust, E. Virginia; Berges, John A.; Bowler, Chris; Green, Beverley R.; Martinez, Diego; Putnam, Nicholas H.; Zhou, Shiguo; Allen, Andrew E.; Apt, Kirk E.; Bechner, Michael; Brzezinski, Mark A.; Chaal, Balbir K.; Chiovitti, Anthony; Davis, Aubrey K.; Demarest, Mark S.; Detter, J. Chris; Glavina, Tijana; Goodstein, David; Hadi, Masood Z.; Hellsten, Uffe; Hildebrand, Mark; Jenkins, Bethany D.; Jurka, Jerzy; Kapitonov, Vladimir V.; [...]
  • imprint: American Association for the Advancement of Science, 2004
  • Published in: Science
  • Language: English
  • ISSN: 0036-8075; 1095-9203
  • Keywords: Research Article
  • Origination:
  • Footnote:
  • Description: <p>Diatoms are unicellular algae with plastids acquired by secondary endosymbiosis. They are responsible for ~20% of global carbon fixation. We report the 34 million-base pair draft nuclear genome of the marine diatom Thalassiosira pseudonana and its 129 thousand-base pair plastid and 44 thousand-base pair mitochondrial genomes. Sequence and optical restriction mapping revealed 24 diploid nuclear chromosomes. We identified novel genes for silicic acid transport and formation of silica-based cell walls, high-affinity iron uptake, biosynthetic enzymes for several types of polyunsaturated fatty acids, use of a range of nitrogenous compounds, and a complete urea cycle, all attributes that allow diatoms to prosper in aquatic environments.</p>