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  1. Zeyen, Patrik René [Author] ; Sippl, Wolfgang [Degree supervisor]; Schutkowski, Mike [Degree supervisor]; Krämer, Oliver [Degree supervisor] Martin-Luther-Universität Halle-Wittenberg

    Untersuchungen zur Synthese und biochemischen Charakterisierung von subtypselektiven Inhibitoren der humanen Histondeacetylasen HDAC8 und 10

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    Halle; Wittenberg, [2021?]

  2. Simoben, Conrad V. [Author]; Ghazy, Ehab [Author]; Zeyen, Patrik [Author]; Darwish, Salma [Author]; Schmidt, Matthias [Author]; Romier, Christophe [Author]; Robaa, Dina [Author]; Sippl, Wolfgang [Author]

    Binding free energy (BFE) calculations and quantitative structure-activity relationship (QSAR) analysis of Schistosoma mansoni histone deacetylase 8 (smHDAC8) inhibitors

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    2021

    Published in: Molecules ; 26(2021), 9, Artikel-ID 2584

  3. Darwish, Salma [Author]; Ghazy, Ehab Mohamed Elbassiony [Author]; Heimburg, Tino [Author]; Herp, Daniel [Author]; Zeyen, Patrik René [Author]; Salem-Altintas, Rabia [Author]; Ridinger, Johannes [Author]; Robaa, Dina [Author]; Schmidtkunz, Karin [Author]; Erdmann, Frank [Author]; Schmidt, Matthias [Author]; Romier, Christophe [Author]; Jung, Manfred [Author]; Oehme, Ina [Author]; Sippl, Wolfgang [Author]

    Design, synthesis and biological characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with anti-neuroblastoma activity

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    7 July 2022

    Published in: International journal of molecular sciences ; 23(2022), 14, Artikel-ID 7535, Seite 1-31

  4. Vaca, Hugo Rolando [Author]; Celentano, Ana María [Author]; Toscanini, María Agustina [Author]; Heimburg, Tino [Author]; Ghazy, Ehab [Author]; Zeyen, Patrik [Author]; Hauser, Alexander-Thomas [Author]; Oliveira, Guilherme [Author]; Elissondo, María Celina [Author]; Jung, Manfred [Author]; Sippl, Wolfgang [Author]; Camicia, Federico [Author]; Rosenzvit, Mara Cecilia [Author]

    The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs

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    2021

    Published in: Public Library of Science: PLoS neglected tropical diseases ; 15(2021), 3, Artikel-ID e0009226

  5. Vaca, Hugo Rolando [Author]; Celentano, Ana María [Author]; Toscanini, María Agustina [Author]; Heimburg, Tino [Author]; Ghazy, Ehab [Author]; Zeyen, Patrik [Author]; Hauser, Alexander-Thomas [Author]; Oliveira, Guilherme [Author]; Elissondo, María Celina [Author]; Jung, Manfred [Author]; Sippl, Wolfgang [Author]; Camicia, Federico [Author]; Rosenzvit, Mara Cecilia [Author]

    The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs

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    Lawrence, Kan.: Public Library of Science, 2021

    Published in: PLoS neglected tropical diseases ; 15, 3 (2021), e0009226

  6. Ibrahim, Hany S. [Author]; Abdelsalam, Mohamed [Author]; Zeyn, Yanira [Author]; Zessin, Matthes [Author]; Mustafa, Al-Hassan M. [Author]; Fischer, Marten A. [Author]; Zeyen, Patrik [Author]; Sun, Ping [Author]; Bülbül, Emre F. [Author]; Vecchio, Anita [Author]; Erdmann, Frank [Author]; Schmidt, Matthias [Author]; Robaa, Dina [Author]; Barinka, Cyril [Author]; Romier, Christophe [Author]; Schutkowski, Mike [Author]; Krämer, Oliver Holger [Author]; Sippl, Wolfgang [Author]

    Synthesis, molecular docking and biological characterization of pyrazine linked 2-aminobenzamides as new class I selective histone deacetylase (HDAC) inhibitors with anti-leukemic activity

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    2022

    Published in: International journal of molecular sciences ; 23(2022), 1, Artikel-ID 369

  7. Zeyen, Patrik René [Author] ; Sippl, Wolfgang [Other]; Schutkowski, Mike [Other]; Krämer, Oliver [Other]

    Untersuchungen zur Synthese und biochemischen Charakterisierung von subtypselektiven Inhibitoren der humanen Histondeacetylasen HDAC8 und 10

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    Halle (Saale): Universitäts- und Landesbibliothek Sachsen-Anhalt, 2021

  8. Simoben, Conrad V.; Ghazy, Ehab; Zeyen, Patrik; Darwish, Salma; Schmidt, Matthias; Romier, Christophe; Robaa, Dina; Sippl, Wolfgang

    Binding Free Energy (BFE) Calculations and Quantitative Structure–Activity Relationship (QSAR) Analysis of Schistosoma mansoni Histone Deacetylase 8 (smHDAC8) Inhibitors

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    MDPI AG, 2021

    Published in: Molecules, 26 (2021) 9, Seite 2584

  9. Darwish, Salma; Ghazy, Ehab; Heimburg, Tino; Herp, Daniel; Zeyen, Patrik; Salem-Altintas, Rabia; Ridinger, Johannes; Robaa, Dina; Schmidtkunz, Karin; Erdmann, Frank; Schmidt, Matthias; Romier, Christophe; Jung, Manfred; Oehme, Ina; Sippl, Wolfgang

    Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity

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    MDPI AG, 2022

    Published in: International Journal of Molecular Sciences, 23 (2022) 14, Seite 7535

  10. Vaca, Hugo Rolando; Celentano, Ana María; Toscanini, María Agustina; Heimburg, Tino; Ghazy, Ehab; Zeyen, Patrik; Hauser, Alexander-Thomas; Oliveira, Guilherme; Elissondo, María Celina; Jung, Manfred; Sippl, Wolfgang; Camicia, Federico; Rosenzvit, Mara Cecilia

    The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs

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    Public Library of Science (PLoS), 2021

    Published in: PLOS Neglected Tropical Diseases, 15 (2021) 3, Seite e0009226

  11. Heimburg, Tino; Kolbinger, Fiona R.; Zeyen, Patrik; Ghazy, Ehab; Herp, Daniel; Schmidtkunz, Karin; Melesina, Jelena; Shaik, Tajith Baba; Erdmann, Frank; Schmidt, Matthias; Romier, Christophe; Robaa, Dina; Witt, Olaf; Oehme, Ina; Jung, Manfred; Sippl, Wolfgang

    Structure-Based Design and Biological Characterization of Selective Histone Deacetylase 8 (HDAC8) Inhibitors with Anti-Neuroblastoma Activity

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    American Chemical Society (ACS), 2017

    Published in: Journal of Medicinal Chemistry, 60 (2017) 24, Seite 10188-10204

  12. Ibrahim, Hany S.; Abdelsalam, Mohamed; Zeyn, Yanira; Zessin, Matthes; Mustafa, Al-Hassan M.; Fischer, Marten A.; Zeyen, Patrik; Sun, Ping; Bülbül, Emre F.; Vecchio, Anita; Erdmann, Frank; Schmidt, Matthias; Robaa, Dina; Barinka, Cyril; Romier, Christophe; Schutkowski, Mike; Krämer, Oliver H.; Sippl, Wolfgang

    Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity

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    MDPI AG, 2021

    Published in: International Journal of Molecular Sciences, 23 (2021) 1, Seite 369