Rolke, David Benjamin
[Verfasser:in]
;
Wolff, Hendrik
[Akademische:r Betreuer:in];
Oppermann, Martin
[Sonstige Person, Familie und Körperschaft];
Grade, Marian
[Sonstige Person, Familie und Körperschaft]
Analyse der Expression von Chemokinen und Chemokinrezeptoren in Kopf-Hals-Tumorzellen
Beschreibung:
Radiotherapy plays an important role in the treatment of malignant head and neck tumors. Chemokines are chemotactic cytokines, which can induce tumor proliferation as well as metastasis, although the influence of chemokines and their signaling pathways via chemokine receptors is not fully understood. Moreover, the radiation-induced expression of chemokines and chemokine receptors is poorly studied. Therefore, the purpose of this work was to analyze the expression of the chemokines of the CC-and CXC-class and their receptors in untreated and in irradiated squamous cell carcinoma of the head...