Wolter, Sarah
[Verfasser:in]
;
Gruber, Oliver
[Akademische:r Betreuer:in];
Gruber, Oliver
[Sonstige Person, Familie und Körperschaft];
Kagan, Igor
[Sonstige Person, Familie und Körperschaft]
Pathophysiological changes of neurofunctional interaction between the dopaminergic reward system and the hippocampus in schizophrenia and bipolar disorder
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Hochschulschrift
Titel:
Pathophysiological changes of neurofunctional interaction between the dopaminergic reward system and the hippocampus in schizophrenia and bipolar disorder
Beschreibung:
Schizophrenia and bipolar disorder are severe psychiatric disorders with an overlap in both genotype and phenotype (Cosgrove & Suppes, 2013). Moreover, patients of both disorders have previously been reported to display abnormalities within the dopaminergic reward system (Ashok et al., 2017; Howes & Kapur, 2009), although the nature of these abnormalities is not yet well understood. While former versions of the dopamine hypothesis of psychosis assumed the dopaminergic system to be hyperactive in schizophrenia patients (van Rossum, 1966), more recent versions suggest that the dopaminergic sy...