• Medientyp: E-Book; Hochschulschrift
  • Titel: Lysosomal and mitochondrial crosstalk : the role of lysosomal signaling on mitochondrial biogenesis and function
  • Beteiligte: Yambire, King Faisal [VerfasserIn]; Milosevic, Ira [AkademischeR BetreuerIn]; Fischer, André [GutachterIn]; Nave, Klaus-Armin [GutachterIn]; Raimundo, Nuno [GutachterIn]; Johnsen, Steven Prof. [GutachterIn]
  • Erschienen: Göttingen, 2017
  • Umfang: 1 Online-Ressource; Illustrationen, Diagramme
  • Sprache: Englisch
  • Identifikator:
  • Schlagwörter: Hochschulschrift
  • Entstehung:
  • Hochschulschrift: Dissertation, Georg-August-Universität Göttingen, 2018
  • Anmerkungen:
  • Beschreibung: Defects in metabolism result in various diseases, with neurodegeneration being one of the most prevalent consequences. Mitochondria and lysosomes are long known to be fundamental for cellular metabolism. In addition to being energy ‘factories’, mitochondria are key cellular signaling platforms, contributing to cellular stress responses like autophagy, apoptosis or cell proliferation. Lysosomes have evolved beyond their ‘waste management’ roles and are now understood to coordinate major processes such as autophagy and nutrient sensing. Although for many years, these organelles were seen as i...
  • Zugangsstatus: Freier Zugang